Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2022
  • Volume: 15
  • Issue: 9

Potential test of Soy-yamghurt against antidiabetic in male white rats (Rattus norvegicus) streptozotocin induced

  • Author:
  • Tien Wahyu Handayani*, Viani Anggi**, Afrizal***, Magfirah****, Joni Tandi*****
  • Total Page Count: 5
  • Page Number: 4139 to 4143

College of Pharmaceutical Sciences, Pelita Mas Palu, Central Sulawesi, 94111, Indonesia

*Corresponding Author E-mail: handayanitienwahyu@gmail.com

**viani.anggi@gmail.com

***thezxemoeng@gmail.com

****magfiralukman@gmail.com

*****jonitandi757@yahoo.com

Online published on 27 February, 2023.

Abstract

Soy-yamghurt is a fermented product of soy and sweet potato juice made from the addition of lactic acid bacteria and is thought to have antioxidant abilities, function to repair pancreatic cells, and reduce blood glucose levels.

This study aims to determine the potential of soy-yamghurt probiotic drinks to decrease blood glucose levels of male white rats (Rattus novergicus).

This study used 30 rats divided into six treatment groups, namely normal control (NaCMC), negative control (streptozotocin+NA CMC), positive control (streptozotocin+glibenclamide), treatment formula 1 (streptozotocin+sweet potato juice+ soybean juice (1:1), formula 2(streptozotocin+sweet potato juice+soybean juice (1:2)), and formula 3(streptozotocin+sweet potato juice+soybean juice (2:1)).

The results showed that the average blood glucose levels were normal control (100.4mg/dL), negative control (298.8mg/dL), positive control (81.2mg/dL), formula 1(178.4mg/dL), formula 2(108.0mg). /dL), formula 3(134.4mg/dL).

soy-yamghurt affects reducing blood glucose levels with an effective formula, namely formula 2 by giving 3.4ml.

Keywords

Soy-yamghurt, Blood glucose levels, Male white rat (Rattus novergicus), Streptozotocin