1Clinical Pharmacology Department Faculty of Medicine, Beni Suef University, Beni Suef, Egypt
2Clinical Pharmacy Department Faculty of Pharmacy, Beni Suef University, Beni Suef, Egypt
3Clinical Pharmacy Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt
4Obstetrics and Gynecology Department Faculty of Medicine, Misr University for Science and Technology, Giza, Egypt
5Pharmacy Practice Department Pharmacy Program, Batterjee Medical College, Jeddah, Saudi Arabia
*Corresponding Author E-mail: shireenpharma@gmail.com
Online Published on 10 October, 2023.
The rate of Diabetes in Egypt has significantly increased, exceeding international rates. The International Diabetes Federation (IDF) listed Egypt among the world's top 10 countries in the number of patients with Diabetes. There are two primary subtypes of Diabetes in pregnancy. One of these is pregestational diabetes mellitus (PGDM), which occurs before a woman becomes pregnant. The second is hyperglycemia, which was first detected during pregnancy and should be classified as DM in pregnancy (DIP) or gestational DM according to WHO guidelines (GDM). DIP is a disease that may be diagnosed if typical DM criteria are reached during screening, while GDM is diagnosed when women satisfy at least one of the criteria during a 100g oral glucose tolerance test, according to current guidelines (OGTT). GDM is a condition that affects pregnant women who develop hyperglycemia but do not have a history of Diabetes.
This prospective study was conducted on ninety pregnant females with normal menstrual cycles before pregnancy. Patient’s demographics, urine and blood analysis, HbA1c and OGTT at 24 weeks gestation, as well as ultrasonic screening for early prediction of any congenital malformations were assayed.
There was a significant difference in terms of Oral glucose tolerance test at week 24 during fasting, Oral glucose tolerance test at week 24 after one hour, Oral glucose tolerance test at week 24 after two hours, Oral glucose tolerance test at week 24 after three hours using 100 gms glucose; p-value <0.05.
The results of this study concluded that mothers with PGDM had worse pregnancy outcomes than those with GDM.
Pregestational diabetes mellitus, International Diabetes Federation
