Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 10

Assessment of Antibacterial, Cytotoxicity and Wound Healing Influence of Copper Nanoparticles Synthesized using Probiotic Bacteria

  • Author:
  • Mervat G. Hassan1, Amr A. El-Waseif2,*, Reem H. Abd El Gawad1, Omnia M. Arief1, Sabah A. Abo El-Maaty1
  • Total Page Count: 6
  • Page Number: 4537 to 4542

1Botany and Microbiology Dept., Faculty of Science, Banha University, Egypt

2Botany and Microbiology Dept., Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

*Corresponding Author E-mail: amrelwaseif@azhar.edu.eg

Online Published on 01 February, 2024.

Abstract

The present article targeted to biosynthesis and description of copper oxide nanoparticles (CuO NPs) using probiotic isolate and assessment the antibacterial, cytotoxicity of these NPs and its effect on wound heals. The CuO NPs are biosynthesized using probiotic isolate identified as Bacillus cereus. These CuO NPs are characterized using UV, FT-IR, Zeta and TEM. The antibacterial efficiency is assayed by agar plate diffusion protocol. Results assured that the CuO NPs can prevent Staphylococcus aureus jointly Escherichia coli growth. MTT procedure exercised to detect cytotoxicity and wound healing effects. The results revealed that CuO NPs can use as antibacterial agent with non-significant effects on host cells and wound healing.

Keywords

Bacillus cereus, Copper oxide nanoparticles, Characterization, Antibacterial impact, Cytotoxicity, Wound healing