Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 10

Antioxidant, Antiinflammatory, and Anti Uric Acid Bioactivity Correlation of some Family Acanthaceae Plants (A Review)

  • Author:
  • Candra Irawan1,2, Berna Elya1,*, Fadlina Chany Saputri1, Heri Setiawan1
  • Total Page Count: 9
  • Page Number: 4959 to 4967

1Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, Indonesia

2Department of Food Nanotechnology, Politeknik AKA Bogor, Bogor, West Java, Indonesia

*Corresponding Author E-mail: berna.elya@farmasi.ui.ac.id

Online Published on 01 February, 2024.

Abstract

Uric acid is a naturally occurring antioxidant that is produced in the body as a byproduct of the enzymatic breakdown of xanthine. Inflammation of the blood vessel cells in the human body can be brought on by abnormally high amounts of uric acid in the serum. An acute inflammatory response often manifests with symptoms similar to those of gout attacks. XO is a major contributor to the production of superoxide free radicals, which are a factor in chronic inflammatory diseases. Existing drugs have been used to treat gout and inflammatory diseases, but have negative effects in humans. Medicinal plants are a source of active chemicals, which are particularly significant in the process of developing new medications due to the variety and distinctive chemical structures of these active compounds. Justicia gendarussa, Andrographis paniculata (Burn.f.) Nees, Ruellia tuberosa L, and Clinacanthus nutans Lindau are examples of plant species in the Acanthaceae family. The results of existing publications show that the bioactive compounds contained in these plants have a relationship between antioxidant activity, anti-uric acid and anti-inflammatory properties.

Keywords

Antioxidant, Anti-inflammatory, Anti uric acid, Acanthaceae