Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 10

Thiazole Ring: A Pharmacological Active Scaffold

Department of Pharmaceutical Chemistry, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela, Ropar, 140111, I. K. G. Punjab Technical University, Kapurthala, Jalandhar, Punjab, India

Abstract

The most important five-membered hetrocyclic molecules with a wide range of biological action are thiazoles. Sulphur atoms are found at position 1 while nitrogen atoms are found at position 3. The goal of this research is to compile a list of activities and innovative methodologies for the synthesis of thiazole derivatives. The entire review discusses thiazole's numerous properties, including antibiotics, antimalarials, antidiabetics, anticancer, anti-inflammatory, diuretics, antimycobactreial, and methods for thiazole synthesis.

Keywords

Synthesis, Thiazole and its derivatives, Biological activities