Research Journal of Pharmacy and Technology

Hippobroma longiflora (L.) G. Don or "kitolod" (Indonesia) is widely known as a traditional food medicine. However, the bioactive constituents of this plant are still unclear. Therefore, we investigated the bioactive compounds of H. longiflora (leaves and flowers) with Gas Chromatography-Mass Spectrometry (GC-MS) and further evaluated their potential biological activity. Ethanol extracts from the flowers and leaves of H. longiflora are targeted for phytochemical profiling of this plant. As a result, 16 metabolite compounds on leaves and 21 on flowers were successfully detected. A total of seven compounds, namely 2, 6, 10, 14, 18, 22-. Tetracosahexaene, 2, 6, 10, 15, 19, 23-hexamethyl-, (all--E)-, 2,6,10-Trimethyl, 14-Ethylene-14-Pentadecne, Stigmast-5-EN-3-OL, Stigmasterol, and Vitamin E dominate in both parts of this plant. The results of phytochemical analysis at the National Institute of Standard and Technique (NIST), H. longiflora can be an essential source of anti-tumor, anti-cancer, antibacterial, and antioxidant drugs.