Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 2

In vivo comparison of volume of interest determination on maxillary bone regeneration in orthodontic treatment: Cone-beam computed tomography versus micro-computed tomography

  • Author:
  • Sudarmono1, Sunardhi Widyaputra2, Suhardjo Sitam3, Inne Suherna4, Fourier Dzar Eljabbar Latief5,6, Arni Diana Fitri7, Arif Rachman8,9,*
  • Total Page Count: 6
  • Page Number: 663 to 668

1Doctoral Degree Program in Military Dentistry Science, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia

2Department of Oral Biology, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia

3Department of Radiology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia

4Department of Pedodontist, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia

5The Physics of Earth and Complex Systems, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung, Indonesia

6Micro-CT Laboratory Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung, Indonesia

7Veterinary Teaching Hospital, IPB University, Bogor, Indonesia

8Department of Cell Biology and Biomolecular, Faculty of Medicine, Indonesian Defense University, Bogor, Indonesia

9Department of Dental and Oral Medicine, Faculty of Medicine, Indonesian Defense University, Bogor, Indonesia

Abstract

Orthodontic treatment can result in relapse, side effects associated with Orthodontic Tooth Movement (OTM) are root resorption, bone loss, and gingival inflammation which impairs long-term stability during orthodontic treatment. OTM creates a gap causing relapse after orthodontic treatment. Regenerate bone to prevent relapse after orthodontic treatment. Volume of interest (VOI) measurement by (3 Dimension) 3D imaging Cone-beam computed tomography (CBCT) or Micro-computed tomography (Micro-CT) in vivo. In vivo tests were carried out on 6 Wistar rats aged 5 months and performed 10gf maxillary Molar 1 (M1) withdrawal with 0.010 inch Nickel-Titanium (NiTi) and 8 mm close coil spring, maxillary separation was carried out by CBCT and Micro-CT tests. The tensile force of the orthodontic appliance in the compressed and tense area is a characteristic of OTM causing changes in remodeling. Alveolar bone displacement can occur when tooth roots move through the alveolar cortical bone occurring during OTM. Measurements on samples from CBCT and Micro-CT to investigate the accuracy and reproducibility of landmarks. CBCT resolution 0.0131 μm / pixel and Micro-CT 5.7 μm/pixel, Micro-CT can determine VOI boundaries. Comparison of VOI from CBCT and Micro-CT showed VOI CBCT 9.99% and VOI Micro-CT 22.22%. 3D Micro-CT visualization is more detailed than CBCT, so VOI can be determined easily and more accurately. Detailed, clear, and accurate 3D Micro-CT visualization in the determination of VOI versus CBCT.

Keywords

CBCT, Micro-CT, Orthodontic Tooth Movement, Volume of Interest, Gap