1Department of Dentistry, Dijlah University College, Baghdad, Iraq
2Department of Dentistry, Al-Rasheed University College, Baghdad, Iraq
3Department of Dentistry, Al-Farabi University College, Baghdad, Iraq
4College of Dentistry, Al-Farahidi University, Baghdad, Iraq
5College of Technical Engineering, The Islamic University, Najaf, Iraq
6Medical Laboratory Techniques Department, Al-Turath University College, Baghdad, Iraq
*Corresponding Author E-mail: h_r200690@yahoo.com, haideralmashhdani@alrasheedcol.edu.iq
Online Published on 11 October, 2023.
Metronidazole-MIPs were prepared by using (MDZ) as the template as well as allylchloride (AYC) or allylbromide (AYB) as monomer, used (TMPTA) tri-methylol propane tri-acrylate or ethylene glycol di-methyl acrylate (EGDMA) as cross-linker and initiator used (BP) benzyl peroxide. By using different plasticizers (di butyl Phthalate (DBPH), Nitrobenzene (NB), oleic acid (OA) and paraffin) for MDZ-MIP1 and (Di-butyl sebecate (DBS), Di-methyl acrylate (DMA), Tributylphosphate(TBP) and Tris(ethylhexyl phosphate (TEHP) ) for MDZ-MIP2. Membranes of MIPs were prepared in PVC matrix. The characterizations of each electrode were determined The Slope range from (55.083 - 43.711) mV/decade, Limit of Detection (8 X 10-4 - 2 X 10-6) and Linearity range of electrodes MIPs from (1 X 10-5 - 1 X 10 -1). Stable Signe of electrode pH from (2.5-9) and study the selectivity with additives of drugs synthesis (Glucose, Calcium stearate, sodium benzoate and benzoic acid) demonstrate strong selectivity.
Metronidazole, Sensor, Ion Selective electrodes (ISEs), MIPs Molecularly imprinted polymers
