Primary prophylaxis of COVID-19: A comprehensive review of approved vaccines

Vaccines were commonly viewed as part of the exit strategy to return to prior employment, education, and socialization routines. It is important to increase the availability of doses for the immunization of the global population in order to control the COVID-19 pandemic, which involves tight cooperation between manufacturers and authorities. A global effort is warranted for the management of the virus and equal access to effective vaccines for all countries. This review examines the immunological responses elicited, safety, and SARS-CoV-2 protection offered by vaccine. This review also explores the essential phases between a promising preclinical trial and production on a large scale. The challenges faced during this pandemic and platforms built to address them during this pandemic will play a crucial role in the containment of future outbreaks. Nearly two years since the start of the pandemic, we are at a point where preclinical and clinical data are generated for vaccines can assist us in gaining a deeper understanding of this important area.