Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 3

Worldwide publication trends of drug repurposing and drug repositioning in the science of medicine (2003-2022)

  • Author:
  • Lalu Muhammad Irham1,*, Zalik Nuryana2, Dyah Aryani Perwitasari1, Yudha Rizky Nuari1, Made Ary Sarasmita5,6, Wirawan Adikusuma3, Haafizah Dania1, Rita Maliza4, Rocky Cheung7
  • Total Page Count: 9
  • Page Number: 1333 to 1341

1Faculty of Pharmacy, University of Ahmad Dahlan, Yogyakarta, 55164, Indonesia

2Department of Islamic Education, Universitas Ahmad Dahlan, Yogyakarta, 55191, Indonesia

3Department of Pharmacy, University of Muhammadiyah Mataram, Mataram, 83127, Indonesia

4Biology Department Faculty of Mathematics and Natural Sciences, Andalas University, Padang, West Sumatra, Indonesia

5Department of Clinical Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan

6Pharmacy Study Program, Faculty of Science and Mathematics, Udayana University, Bali, Indonesia

7Department of Chemistry and Biochemistry, University of California, Los Angeles, USA

*Corresponding Author E-mail: lalu.irham@pharm.uad.ac.id

Online Published on 12 October, 2023.

Abstract

Science of medicine in the post-genomic era has significantly enhanced the knowledge of human diseases. These advancements could shed light to the translation of these benefits into drug therapeutics. Drug repurposing is a strategy that plays a pivotal role to provide novel insights into disease biology and further drive drug discovery as the ultimate goal. Herein, the current study aimed to analyse the global trends of drug repurposing peer-review publications from 2003 until 2022.

We retrieved 1.371 articles related to drug repurposing studies and used similar terms and keywords, including “drug repositioning”, “drug repurposing”, “drug reprofiling”, “drug reusing”, and “drug recycling”.

The number of drug repurposing publications has increased dramatically from 2003 through 2022. Besides, the most active country in publishing drug repurposing research is the United States, followed by China, India, the United Kingdom, and Italy, respectively. Meanwhile, the top five frequently used keywords are drug repurposing (n = 336), drug repositioning (n = 335), COVID-19 (n = 134), SARS-CoV-2 (n = 135), and molecular docking (n = 67).

This study emphasizes the importance of conducting active research collaboration in drug repurposing and drug repositioning especially pertaining to the COVID-19 pandemic.

Keywords

Drug repurposing, Drug repositioning, Drug discovery, Drug reusing, Molecular docking, Bibliometric