Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 6

The measurement of Candida albicans Tolerance under the influence of Moringa oleifera

  • Author:
  • Sri Rezeki1,*, Basri A. Gani2, Munifah Abdat3, Ridha Andayani2, Fitri Yunita Batubara4, Nur Asmah5, Chusnul Chotimah6
  • Total Page Count: 5
  • Page Number: 2579 to 2583

1Oral Medicine Department Faculty of Dentistry, Universitas Syiah Kuala, Darussalam, Banda Aceh, Aceh, Indonesia

2Oral Biology Department Faculty of Dentistry, Universitas Syiah Kuala, Darussalam, Banda Aceh, Aceh, Indonesia

3Department of Dental Public Health, Faculty of Dentistry, Universitas Syiah Kuala, Darussalam, Banda Aceh, Aceh, Indonesia

4Department of Conservative Dentistry, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Sumatera Utara, Indonesia

5Department of Conservative Dentistry, Faculty of Dentistry, Universitas Muslim Indonesia, Makasar, Sulawesi Selatan, Indonesia

6Department of Protodonsia, Faculty of Dentistry, Universitas Muslim Indonesia, Makasar, Sulawesi Selatan, Indonesia

*Corresponding Author E-mail: iy_99fkg@usk.ac.id

Online Published on 17 October, 2023.

Abstract

Natural ingredients such as M. oleifera have antibacterial and antifungal properties.The fungistatic and bacteriostatic properties are highly desirable for commensals.The tolerance properties of antifungals help create a balance among oral commensals such as Candida albicans (C. albicans). This study aimed to examine the tolerance properties of M. oleifera to C. albicans regarding biomass, pH stability, biostability, absorption, and opsonization properties. This study used Moringa leaves (M. oleifera) extracts and C. albicans as subjects. Tolerance properties were checked with analytical balance, pH meter, Sabouraud dextrose agar (SDA) medium, spectrophotometer, and 1% crystal violet. M. oleifera extracts at concentrations of 10% and 5% had excellent tolerance properties of index biomass properties, pH stability, biostability, absorption and residue, and opsonization. The M. oleifera have tolerance properties for C. albicans and significant differences between the concentrations tested. M. oleifera extract has good tolerance properties to C. albicans as an oral commensal.

Keywords

Candida albicans, Moringa oleifera, Tolerance