Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 6

A comparative evaluation of the enamel remineralizing potential of self assembling peptide, nanohydroxyapatite toothpaste and duraphat fluoride varnish - An In vitro study

  • Author:
  • Natasha Shetty*, Shravan Kini**, Prathap M S Nair***, Vivian Flourish D’Costa****, Nishi Jayasheelan*****
  • Total Page Count: 5
  • Page Number: 2900 to 2904

Department of Conservative Dentistry and Endodontics, Yenepoya Dental College, Yenepoya (Deemed to be University), Deralakatte, Mangalore - 575018, Karnataka, India

*Corresponding Author E-mail: drnatashashetty@gmail.com

**drshravankini@gmail.com

***prathapmsnair@gmail.com

****drvivianflourish@gmail.com

*****dr.nishi.j@gmail.com

Online Published on 17 October, 2023.

Abstract

48 freshly extracted human premolars were selected and divided into 1 control and 3 experimental groups (n = 12/group) as follows: group 1, artificial saliva; group 2, treatment with self-assembling peptide; group 3, treatment with nanohydroxyapatite; group 4, treatment with duraphat fluoride varnish. The treated teeth were assessed under SEM, Vickers Hardness and DIAGNODENT analysis. The data were analyzed with one way Anova/Kruskall - Wallis analysis (P<.05). Self-assembling peptide (Curodont gel) showed highest remineralization of the artificially created white spot lesions followed by Duraphat fluoride varnish and Nanohydroxyapatite (Apagard) toothpaste at the end of 90 days.

Keywords

Remineralization, Self-assembling peptides, Nanohydroxyapatite, White spot lesions, Duraphat, Fluoride Varnish