Department of Biochemistry and Microbiology, Faculty of Pharmacy, Aleppo University, Syria
*Corresponding Author E-mail: samihematology@gmail.com
Online Published on 25 January, 2024.
Many studies on type 2 diabetes had conflicting results about the prognostic importance of the ABO or Rhesus (Rh) D expression, and in this context, the other important types of Rh were never studied.
The purpose of this study was to investigate whether ABO and Rh phenotype has an association with vascular complications in type 2 diabetes.
390 individuals were included in this study (194 were type 2 diabetic patients and 196 were healthy persons). 159 of diabetic patients were classified into two groups: group DC which included 98 diabetic patients with vascular complications, and group D which included 61 diabetic patients without vascular complications. A slide agglutination test was done to determine the ABO and Rh types.
While no difference was observed between the frequency of any ABO or Rh types between patients and healthy people, the frequency of A-type and each Rh+ type was higher in the DC group compared to the D group. In addition, the prevalence of the Rh DCceand Rh DcEphenotypes was higher in the DC group.
Determining the phenotype of the Rhesus blood group may be a cheap and easy prognostic test for vascular complications development in type 2 diabetes.
Type 2 diabetes, ABO blood group, Rhesus blood group, Vascular complications, Prognostic test
