1Department of Chemistry, R.V.R. and J.C. College of Engineering, Guntur, Andhra Pradesh, India
2Department of Chemistry, S.V. University, Tirupathi, Andhra Pradesh, India
*Corresponding Author E-mail: srinunarala@gmail.com
Online Published on 25 January, 2024.
A simple, sensitive extractive spectrophotometric method for the determination of Meropenem has been proposed. The method is based on the formation of an ion-association complex between the drug and acidic dye methyl orange, which was a pale yellow colored chromogen extracted with dichloro methane from the aqueous phase, measured at 400 nm. The Beer’s law was obeyed in the concentration range of 10 - 30 μg/ml. Thus results of the proposed method was validated statistically and applied successfully to the determination of Meropenem in bulk and its dosage forms.
Meropenem, Extractive Spectrophotometry, Recovery experiments
