Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2023
  • Volume: 16
  • Issue: 9

Preliminary phytochemical screening and antioxidant properties of methanolic root extract of Picrorhiza kurroa

  • Author:
  • Subbulakshmi Packirisamy1,*, Valli Gunam2, Jaideep Mahendra3, Deepa Rajendran4, Ponnulakshmi Rajagopal5
  • Total Page Count: 5
  • Page Number: 4266 to 4270

1Lecturer, Department of Pharmacology, Meenakshi Ammal Dental College and Hospital, Maduravoyal, Chennai, Tamilnadu

2Professor, Department of Pharmacology, Meenakshi Ammal Dental College and Hospital, Maduravoyal, Chennai, Tamilnadu

3Professor, Department of Periodontology, Meenakshi Ammal Dental College and Hospital

4Associate Professor, Department of Biochemistry, Madha Dental College and Hospital, Kundrathur, Chennai, Tamilnadu

5Scientist, Central Research Laboratory, Meenakshi Ammal Dental College and Hospital, Maduravoyal, Chennai, Tamilnadu

*Corresponding Author E-mail: subbulakshmi@madch.edu.in, subbu.buvi@gmail.com

Online Published on 25 January, 2024.

Abstract

Picrorhiza kurroa Royle ex Benth. (Scrophulariacae) is a herb in the Ayurvedic system of medicine highly noted for its hepatoprotective effect. Over exploitation for various medicinal purposes has made the rhizome as an endangered species. In spite of its geographical distribution, it is available in all the herbal drug stores. The rationale behind this study is to authenticate and standardize the Picrosides by different parameters to enable its identity, purity and efficacy. Thus, the Present study analyzed the presence of phytochemicals qualitatively and evaluated the antioxidant properties in the methanolic extracts of Picrorhiza kurroa.

Preliminary analysis of phytoconstituents of root parts of this plant using the standard procedures and Antioxidant properties were determined by 1,1- diphenyl,2-picrylhydrazyl (DPPH) assay.

The qualitative phytochemical analysis revealed the presence of secondary active constituent’s such as glycosides, cardiacglycosides, Tannins, terpenoids, steroids and coumarins and also possesses high free radical scavenging property.

Therefore this study explored the antioxidant properties which strongly supports that could prevent many free radical related disorders. Also paves the way for further quantitative and animal studies, planned to explore the molecular mechanisms for the study based on cardiovascular disorders.

Keywords

Bioactive compounds, Qualitative analysis, Herbal medicine, Antioxidant, DPPH, Picrosides, Phytochemical screening, Picrorhiza kurroa