Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 1

Characterization of structural, antimicrobial activity, of coriander seed oil

  • Author:
  • Wijdan Amer Ibrahim*, Ekhlas Abdallah Hassan**, Wafaa Sh. Al-Zuhairi***
  • Total Page Count: 6
  • Page Number: 265 to 270

Department of Chemistry, College of Science, University of Diyala, Diyala, Iraq

*Corresponding Author E-mail: wijdan.amer84@gmail.com

**ekhlasbiochemistry@gmail.com

***wafaa.chem@gmail.com

Online published on 31 May, 2024.

Abstract

This study was aimed to investigate the structure of bioactive components of Coriander Seed Oil (CSO) and their antimicrobial effects. Initially, the structural examination was conducted using various spectroscopic techniques, such as FTIR, and UV-visible spectroscopy, which are important in determining substituents, functional groups, and the presence of conjugated double bonds in CSO. From the FTIR spectra, a variety of sharp, strong, and weak peaks were specified relating to the main components of Linalol, and Decenolin CSO. The results of UV-visible spectroscopy confirmed the presence of Linalool as a major compound, and conjugated double bonds were also found. Furthermore, anti- microbial activity of CSO was studied against various types of bacteria. Strong bacterial inhibitory effects were observed, especially against S. aureus, with an average inhibition zone of 18 mm. It was also found from the structural characterization of CSO that the existence of Linalol is responsible for potential antibacterial activity. The main observation of this work is that CSO has antimicrobial activity even against methicillin-resistant Staphylococcus aureus.

Keywords

Coriander Seed Oil, Antimicrobial, Linalol, Decenol, Staphylococcus