Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 10

Isolation of β-amyrin and glycyrrhetinic acid from petroleum ether extract of Corchorus depressus (Linn.) leaves

1Assistant Professor, Department of Engineering Sciences and Humanities, Sandip Institute of Technology and Research Centre, Mahiravani, Trimbak Road, Nashik (M.S.), India - 422213

2Principal, Poojya Sane Guruji Vidya Prasarak Mandal’s S. I. Patil Arts, G. B. Patel Science and Shahada Taluka Kharedi Vikri Sangh Commerce College, Shahada, Dist - Nandurbar (M.S), India - 425409

Abstract

Corchorus depressus (Linn.) is a member of the Tiliaceae family, which has approximately 100 distinct species. The whole plant research of Corchorus depressus (L.) showed promise due to separated phytochemicals, possible biological activity, and medicinal utility. Corchorus depressus (Linn.) is a perennial herb found widely in South Asia and South America. The whole plant exhibits an important therapeutic significance. We recently reported the preliminary phytochemicals screening and the biological activity of various solvent-based extracts of the Corchorus depressus (Linn.) leaves, including antibacterial, antifungal, anti-inflammatory, and anti-oxidant properties. In the pursuit of the new bioactive compounds, we conducted the detailed phytochemical investigation for the Petroleum ether extract of Corchorus depressus (Linn.) leaves. The phytochemical analysis revealed to the discovery of a novel triterpene saponin, β-amyrin, and its pentacyclic triterpenoid derivative Glycyrrhetinic acid. Melting points, chemical analyses, and spectral analysis were used to identify the compounds.

Keywords

Tiliaceae, Corchorus depressus, Petroleum ether extract, β-amyrin, Glycyrrhetinic acid