A review on design of coumarin hybrids in the treatment of breast cancer

The breast cancer is one of most prevalent cancer in women, and after lung cancer, it is the second greatest death cause in women. From previous years, progress has been made and continues to be made in the breast cancer vaccines development. It is a great approach to create hybrid compounds by combining distinct pharmacophores to gain important biological activity. The use of coumarin in conjunction with other themes has resulted in the creation of novel strategies to combat breast cancer. Coumarin has been shown in reviewed literature to be a potent antidote for breast cancer, binding to different biological targets linked to the disease. The hybrids of Coumarin have recently gained the notice of researchers who want to investigate their therapeutic potential in the treatment of breast cancer due to their minimal toxicity in multiple organ systems. Interactions with isoxazoles, thiazoles, monastrol, chalcone, triazole, sulphonamide, and other coumarin strains have been reported. The definitions of the different coumarin compounds, as well as their structural connections, are described in this review article.