Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 10

Machine vision based quality inspection of pharmaceutical bottle packaging

  • Author:
  • Bhoomika Shetty1,*, S M Madhushree1,**, B.S Muddukrishna2,***, Ravindra Shenoy3,****, H Kirankumar4,*****, Mahendra Joshi5,7,******, Girish K Pai6,*******
  • Total Page Count: 7
  • Page Number: 5154 to 5160

1Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal

2Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal

3Department of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal

4Department of Commerce, Manipal Academy of Higher Education (MAHE), Manipal

5Vice President – Corporate Development, Ingenus Pharmaceuticals LLC, 100 Ford Rd, Denville, New Jersey, 07834, USA

6Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal

7Research and Development, IDRS Labs Pvt. Ltd., Bangalore, Karnataka, India

*Corresponding Author E-mail: bhoomika.shetty1@learner.manipal.edu

**madhushree0505@gmail.com

***krishna.mbs@manipal.edu

****ravindra.shenoy@manipal.edu

*****kiran_kch@yahoo.com

******mahendra.joshi@idrslabs.com

*******girish.pai@manipal.edu

Online published on 6 May, 2025.

Abstract

The packaging of the drug products depends on the dosage form and the market in which they are to be commercialized. Based on the market, some tablets/capsules are packed in HDPE/PET bottle containers. Packaging plays a crucial role in maintaining product safety, purity, quality, and stability from production until it reaches customers. Ensuring the packaging and product quality are within specifications is essential during the packaging operation. Equipment utilized in the bottle packaging process is employed with many automated controls such as Machine Vision systems, which work on image acquisition principles along with Deep Learning (DL) and Artificial Intelligence (AI) to identify the defects during the process and reject imperfect packaging. MV is one of the leading pillars of Pharma 4.0, which focuses on digitalization and automation in the pharmaceutical manufacturing industry. This paper discusses the latest advancements and applications of MV in pharmaceutical solid dosage form bottle packaging.

Keywords

Machine Vision, Pharmaceutical Bottle Packaging, Image Acquisition, Pharma 4.0, Quality Inspection