Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 12

Preclinical evaluation of pods of Ageratina adenophora for its rudimentary fatal activity

  • Author:
  • Mrityunjoy Majumdar1, Nilendu Sekhar Sarkar2, Debapriya Das1, Arnab Samanta3, Sourav Roy1, Prodip Roy1,*, Soumyadeb Dutta1
  • Total Page Count: 5
  • Page Number: 6003 to 6007

1Department of Pharmacology, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia, West Bengal, India741222

2Indoriv Clinical Private Limited, 87, Chowringhee Road, Kolkata, 700020, West Bengal, India

3Department of Pharmaceutics, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia, West Bengal, India741222

*Corresponding Author E-mail: prodiproy19951228@gmail.com

Online published on 9 May, 2025.

Abstract

Ending a pregnancy is quite common these days. In developing countries, there are much more cases termed as unsafe abortion. Some standard drugs are already available in the market, most of them are possessing high level of toxicity and expensive. There is always search for a new drug which is safe and cost effective. Ageratina adenophora is a medicinal plant in the Asteraceae family. It mainly contains alkaloids. In this experiment, the study was focused on evaluating the abortifacient effect of Ageratina adenophora. The hydroalcoholic extract of the pods of Ageratina adenophora was formed by the maceration process. The extract has shown a promising effect as an abortion-inducing agent while compared with the standard drugs. The animals treated with the extract of Ageratina adenophora has decreased the abortion time within 15.01 hrs with 85.22 percent fatality in offspring which is noteworthy. The research outcomes indicate that the hydroalcoholic extract of the pods of the Ageratina adenophora has shown significant abortifacient activity.

Keywords

Ageratina adenophora, Abortion, Abortifacient, Fatality