Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 2

Micro hydroxyapatite in bone regeneration: A literature review

  • Author:
  • Shafira Kurnia Supandi*, Ni Luh Desy Ayu Susilahati, Lubna, Yasmin Firdausi Rezkika, Agung Krismariono, Ernie Maduratna
  • Total Page Count: 4
  • Page Number: 591 to 594

Department of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya - Indonesia

*Corresponding Author E-mail: shafira-k-s@fkg.unair.ac.id

Online published on 1 June, 2024.

Abstract

Periodontal ailment is in a way the most frequent disorder that humanity faces. Severe periodontitis, which affects roughly 743 million people globally around the world, is the sixth-grade greatest prevalence (11.2%) of any illness. Hydroxyapatite (HA) is a major element for bone regeneration. Biocompatibility, bioactivity, low degradation, osteoconduction, osteointegration, and osteoinduction are all big benefits of HA. Osteoinduction is a system wherein osteoprogenitor cells are stimulated to turn into osteoblasts, which then start the development of new bone.

This study provides a complete overview of the history and evolution of the use of HA for various regeneration applications, as well as evolving trends.

By using HA as a scaffold for osteoinduction, osteoprogenitor cells are stimulated to form osteoblasts, which subsequently initiate the construction of new bone.

Keywords

Bone regeneration, Micro hydroxyapatite, Medicine, Osteoconduction