Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 2

Biogenic synthesis of copper nanoparticles from flower extract and their cell cytotoxic potential

  • Author:
  • Ajay Kasivishwanathan Chandrasekar1, Nishu Sekar2,**, Selvakumar Dharmaraj1, Hariprasath Lakshmanan1,*
  • Total Page Count: 6
  • Page Number: 763 to 768

1Division of Biochemistry, School of Life Sciences (Ooty off-campus), JSS Academy of Higher Education and Research, Longwood, Mysuru Road, Ooty, 643001, The Nilgiris, Tamilnadu

2Division of Biotechnology, School of Life Sciences (Ooty off-campus), JSS Academy of Higher Education and Research, Longwood, Mysuru Road, Ooty, 643001, The Nilgiris, Tamilnadu

*Corresponding Author E-mail: hariprasath80@jssuni.edu.in

**nishu@jssuni.edu.in

Online published on 1 June, 2024.

Abstract

In order to overcome the negative potential risks of conventional nanoparticles and achieve the goal of human therapeutic uses, sustainable nanoparticles must be synthesized. In this paper, we have created a simple method for producing copper nanoparticles using green chemistry. With the use of Cassia auriculata's floral aqueous extract, copper nanoparticles (CuNPs) were effectively produced. In a UV-Visible Spectrophotometer, sythesized CuNPs detect absorbance at 276 nm, a hallmark of copper nanoparticles. The relevant functional groups involved in lowering and stabilizing CuNPs were found using Fourier Transform Infrared Spectroscopy. CuNPs shape, crystalline phase, and elemental composition were seen using scanning and transmission electron microscopy, energy dispersive analysis spectroscopy, and other techniques. Moreover, CuNPs' antibacterial and antifungal properties produced good inhibitory action against the pathogens that were put to the test. Furthermore, at low doses, CuNPs had no effect on the cytotoxicity of the cell lines MDCK and Caco-2. CuNPs may thus be turned into nano-drugs for the treatment of infectious diseases and tumour research.

Keywords

Cassia auriculata L, Copper Nanoparticle, Antibacterial, Antifungal, Cytotoxicity