Antiproliferative effects of C. aromatica extracts and essential oils in MDA-MB231 as a breast cancer cell line

Curcuma aromatica is a species of the Curcuma genus of flowering plants in the ginger family, Zingiberaceae. It is commonly known as wild turmeric, and is native to Southeast Asia, particularly India and Sri Lanka. It is traditionally used in Ayurvedic and other traditional systems for its anti-inflammatory, antioxidant, and antimicrobial properties. In the present research study, the antiproliferative activity was assessed for C. aromatica rhizome extract, rhizome essential oil and leaf oil individually. The results clearly demonstrated the efficacy of C. aromatica extracts and essential oils as a antiproliferative effect towards MDA-MB231, the Breast cancer cell line. The reduction in the cell viability of the breast cancer cell lines on treating with the extracts and essential oils individually can be attributed to Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin and unique odour defining components such as cedrene, Xanthorrhizol, camphor, Germacrone, Isofuranogermacrone and 1,8-cineole. The study clearly demonstrates the antiproliferative effects of C. aromatica.