Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 4

Development and characterization pioglitazone hydrochloride loaded nanoparticle for management of diabetes mellitus

  • Author:
  • Kedar Prasad Meena*, Bishesar Kumar Sahu, Tripty Karri, Pradeep Samal, Sandeep Yadav, Divya Jaiswal
  • Total Page Count: 5
  • Page Number: 1748 to 1752

Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur - 495009, C.G., India

Abstract

The potential applications of nanoparticles as oral drug delivery systems for diabetes treatment are discussed in this research article. This paper discusses polymeric nanoparticles, polysaccharides, and polymeric nanoparticles in the oral administration of anti-diabetic drugs. Diabetes is a chronic metabolic disorder characterized by insulin deficiency. Diabetes treatments are numerous, and nanoparticles have several advantages. Several studies and research reports based on nanotechnological approaches in the formulation of anti-diabetic drugs have highlighted the fact that research in the formulation of nanodrugs improved diabetes-fighting strategies based on plausible molecular mechanisms of action of the drugs. Additionally, efforts have been made to determine the optimal drug concentration and time of exposure in order to recommend a scientifically validated drug dose response in the development of various therapeutic strategies for anti-diabetic drugs, various types of nanoparticles are available; polymeric nanoparticles are one of the most commonly used nanoparticles. Polymeric nanoparticles range in size from 10-1000 nm. Polymeric nanoparticles created by combining a drug and a polymer. The main advantages of polymeric nanoparticles are their ease of preparation, targeted delivery, dose minimization, and high therapeutic efficiency.

Keywords

Anti-diabetic, Hypoglycemic drug, Polymeric nanoparticles, Polymers, Pioglitazone, Oral delivery, Solvent evaporation method