Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 4

Effect of α-mangostin from Garcinia mangostana on osteoblast cells in the wound healing process: A review

  • Author:
  • Ardian Jayakusuma Amran1, Defi Marizal1, Ayu Annafi2, Devina Farahamida2, Andra Rizqiawan3,*
  • Total Page Count: 6
  • Page Number: 1885 to 1890

1Resident of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

2Undergraduated Student of Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

3Staff of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

Abstract

Preservation of the socket after a tooth extraction is necessary to maintain the dimensions of the alveolar bone. In addition, it can speed up the healing process while preventing bone resorption. Previous research has shown that α-mangostin contained in mangosteen (Garcinia mangostana) rind can reduce alveolar bone resorption, while accelerating the bone healing process. The purpose of this study is to describe the relationship between the inflammatory process and osteoblastic differentiation after administration of α-mangostinto osteoblast cells.The inflammatory process decreased and osteoblast differentiation increased after the application of alpha-mangostin to osteoblast cells.

Keywords

Alpha-mangostin, Bone healing, Human and health, Medicine, Osteogenesis