1Department of Pharmacology, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, West Bengal, India, 741222
2Department of Pharmaceutics, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, West Bengal, India, 741222
3Veterinary Officer, Block Animal Health Centre, Chanditala - I Block, Masat, Hooghly, 712701
4Department of Veterinary Pathology, West Bengal University of Animal and Fishery Sciences, West Bengal, 700037
*Corresponding Author E-mail: prodiproy19951228@gmail.com
Online published on 29 April, 2025.
In the present research worka herbal formulation prepared from Kalmegh IP (Andrographis paniculata), containing andrographolide and choline chloride, was evaluated for its hepatoprotective activity on poultry chickens by using alcohol induced hepatotoxicity model. Ten days old poultry chicks were selected for the study where Silymarin was taken as the standard drug. After completion of the treatment (25 days), thiopentone sodium induced sleeping time, SGOT, SGPT, ALP, percentage increase in total body masswere evaluated and liver histology was conducted. The formulation showed significant hepatoprotective activity similar tothat ofstandard drug Silymarin.
Andrographis paniculata, Hepatoprotective, Poultry chicken, Choline Chloride