Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 7

Evaluation of hepatoprotective activity of a formulation containing Andrographolide (AGP) and choline chloride on poultry chickens

  • Author:
  • Mrityunjoy Majumdar1, Arnab Samanta2, Avishek Bhattacharjee1, Rituparna Manna1, Marzia Fazal1, Pinaki Das3, Samiran Mondol4, Prodip Roy1,*, Sourav Roy1
  • Total Page Count: 4
  • Page Number: 3181 to 3184

1Department of Pharmacology, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, West Bengal, India, 741222

2Department of Pharmaceutics, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, West Bengal, India, 741222

3Veterinary Officer, Block Animal Health Centre, Chanditala - I Block, Masat, Hooghly, 712701

4Department of Veterinary Pathology, West Bengal University of Animal and Fishery Sciences, West Bengal, 700037

*Corresponding Author E-mail: prodiproy19951228@gmail.com

Online published on 29 April, 2025.

Abstract

In the present research worka herbal formulation prepared from Kalmegh IP (Andrographis paniculata), containing andrographolide and choline chloride, was evaluated for its hepatoprotective activity on poultry chickens by using alcohol induced hepatotoxicity model. Ten days old poultry chicks were selected for the study where Silymarin was taken as the standard drug. After completion of the treatment (25 days), thiopentone sodium induced sleeping time, SGOT, SGPT, ALP, percentage increase in total body masswere evaluated and liver histology was conducted. The formulation showed significant hepatoprotective activity similar tothat ofstandard drug Silymarin.

Keywords

Andrographis paniculata, Hepatoprotective, Poultry chicken, Choline Chloride