1Department of Chemistry, Graphic Era Hill University, Dehradun, Uttarakhand, 248002, India
2Department of Chemistry, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, 248002, India
3Department Mechanical Cluster, School of Advanced Engineering, UPES, Dehradun, Uttarakhand, 248007, India
4Research Scholar, Department of Geography, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi
*Corresponding Author E-mail: drckb2012@gmail.com
Online published on 29 April, 2025.
In this research, Cr(III) and Cobalt (II) complexes were synthesized by a chemical reaction between metallic nitrate and ligand alprazolam and metal complexes with the expected formulas ‘[(L)M(NO3)3], [(L) M(NO3)2]’ in this formula M is Cr (III) and Co (II) accordingly and L is Alprazolam ligand. The characterization of complexes has been done by elemental analysis, IR studies, and thin-layer chromatography. Spectral studies of metal complexes of Cr (III) and Cobalt (II) depict the tridentate and bidentate nature with the drug alprazolam ligand. The present research showed that the antimicrobial activity of the Co (II) metal complex is greater than the Cr (III) metal complex. Metal complexes showed higher antimicrobial activity in comparison to the used ligand (Alprazolam).
Antimicrobial studies, Metal complexes, Benzodiazepine drug, Alprazolam ligand and IR studies
