Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 8

Antipyretic, Antidiabetic and Irritant studies on the Methanolic Extracts and Polyherbal Mixture of Breynia disticha J.R. Forst. and G. Forst. and Vernonia elaeagnifolia DC

  • Author:
  • Saad Touqeer1,2,*, Sulayman Abid3, Muhammad Asad Saeed4, Umair Ikram Dar5
  • Total Page Count: 5
  • Page Number: 3658 to 3662

1College of Pharmacy, Al Ain University, Abu Dhabi, P.O. Box 112612, United Arab Emirates

2AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, P.O. Box 112612, United Arab Emirates

3Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan

4Faculty of Pharmacy, University of Central Punjab, Lahore, Pakistan

5Lahore College of Pharmaceutical Sciences, Lahore, Pakistan

Abstract

An extensive study was conducted on the methanolic extracts of two plants namely, Breynia disticha and Vernonia elaeagnifolia aiming to identify their antipyretic, hypoglycemic and irritant activities. Antipyretic effect was studied using milk induced pyrexia in rabbits whereas hypoglycemic effect was studied using glibenclamide as a standard drug in rabbits. In case of both studies the results were found to be significant (P<0.05). No irritant effect was observed on the rabbit’s ear. The studies show the plants to be of wide and significant medicinal importance.

Keywords

Extracts, Fever, Irritant, Rabbits, Plants, Activity