Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 8

Potential effect of Yemeni Sidr Honey on the Viability of Gingival Fibroblasts and Osteoblast Cells

  • Author:
  • Huda Rashad Qaid1, Mohammed Ahmed Aljunaid2,3, Nejva Kaid4, Rini Devijanti Ridwan5,*, Hendrik Setia Budi5, Arinda Mutiara Bilqis6, Siti Adinda Wulandari6, Indeswati Diyatri5, Shuhdi G. Alaghbari3
  • Total Page Count: 5
  • Page Number: 3764 to 3768

1Doctoral Program of Dental Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

2Faculty of Oral and Dental Medicine, Alsaeed University, Taiz, Yemen

3Department of Dental Medicine, Faculty of Medicine, Taiz University, Taiz, Yemen

4Doctoral of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey

5Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Indonesia

6Undergraduate Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

*Corresponding Author E-mail: rini-d-r@fkg.unair.ac.id

Online Published on 30 April, 2025.

Abstract

Background/aim: The aim of this research is to investigate the potential beneficial effects of Yemen Sidr honey on human gingival fibroblast and osteoblast cell viability and proliferation. Materials and methods: MTT assays were conducted, and the cells were analyzed using an ELISA reader at 590nm. Cell viability was determined based on the optical density readings. Results: At a lower concentration 5μL, the fibroblast and osteoblast cells exhibited a cell viability percentage of over 50%. Conclusion: Yemen Sidr honey is biocompatible and non-toxic to the cultured fibroblast and osteoblast cells.

Keywords

Biocompatible, Human Gingival Fibroblast, MTT assay, Medicine, Osteoblast, Yemen Sidr honey