Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2024
  • Volume: 17
  • Issue: 8

Exploring the Therapeutic potential of Purified Alternanthera pungens Plant Extract

  • Author:
  • Amit Lath1, Sanjit Boora1, Jitendra Kumar Sharma1, Khem Chand2, Samander Singh1, Anita Rani Santal2,*, Nater Pal Singh1,**
  • Total Page Count: 5
  • Page Number: 3869 to 3873

1Centre for Biotechnology, Maharshi Dayanand University, Rohtak - 124001, Haryana, India

2Department of Microbiology, Maharshi Dayanand University, Rohtak - 124001, Haryana, India

*Corresponding Author E-mail: anita.micro@mdurohtak.ac.in

**npsinghcbt@gmail.com

Online Published on 30 April, 2025.

Abstract

This study investigates the cytotoxicity of a purified extract obtained via reverse-phase high-performance liquid chromatography (HPLC) from A. pungens. The purification procedure was particularly executed to isolate bioactive compounds. In vitro Cytotoxicity assessments were performed on MDCK (Madin-Darby canine kidney). The outcomes revealed that the purified extract exhibited no notable cytotoxicity activity against these cells. GC-MS analysis is performed to identify and elucidate the chemical composition of the purified extract this characterization offers valuable insights into the chemical profile of A. pungens and lays the foundation for further research on its pharmacological applications.

Keywords

Cytotoxicity, Alternanthera pungens, MDCK, Reverse-phase HPLC, GCMS analysis