Research Journal of Pharmacy and Technology

Serum has the advantage of having a high concentration of active ingredients so that the skin absorbs the effect the skin more quickly. Licorice root (Glycyrrhiza glabra) has skin-lightening agents. Glabridin is a compound that is productive as a skin lightener. This study aimed to determine the Formulation and evaluation of licorice root (G. glabra) ethanol extract serum as a facial brightener. The experimental procedure is to extract licorice simplicia by maceration method. Evaluation of the preparation includes organoleptic, pH, viscosity, spreadability, homogeneity, stability, and irritation test. We are testing skin-lightening activity using a skin tone chart. The evaluation results of the formulation meet the requirements of good serum, and the viscosity test meets the needs of SNI (16-4399-1996). The results showed that formulation III, containing 20% extract, had the best effect on facial brightening activity, marked by a change in skin color before use from 7 to 3. The results of statistical analysis using Kruskal Wallis and Paired Sample Test. The serum formulation with the addition of 20% licorice root extract had the highest facial brightening effect and was not significantly different from the positive control X.