Very Low Achievement of LDL-C Targets Based On 2019 ESC Guidelines and Factors Associated with Low Achievement of LDL-C Target

The 2019 ESC guidelines recommend more aggressive LDL-C reduction relative to the 2016 guideline. Despite the high prevalence of CVD in Indonesia, there are no publications on the attainment of LDL-C level consistent with the ESC 2019 guidelines. This research aims to examine LDL-C objectives and the the key determinants affecting their attainment. The study procedures were carried out using a prospective cross-sectional method in a tertiary hospital. The sample population consisted 304 patients, with the majority being males (69.41%) aged 56-70 years (57.24%). The results indicated that merely 5.59% of patients attained LDL-C target, including 15 with very high risk (4.93%) and 2 with high risk (0.66). In addition, the influential factors in this study were male (OR 5.680), not smoking (OR 3.080), and adherence (OR 3.441). These results showed that achievement was very low based on the 2019 ESC guidelines. Therefore, further intervention from health professionals was needed to enhance the number of patients attaining the LDL-C objective.