Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 11

The Paris System for Urine Cytology in Urothelial Neoplasms: A Comparative Study with Histopathological Correlation

  • Author:
  • Bibendu Bal1, Aparajita Mishra2, Atanu Kumar Bal3,*, Devidutta Ramani Ranjan Rout4, Sashibhusan Dash5
  • Total Page Count: 6
  • Published Online: Mar 31, 2026
  • Page Number: 5509 to 5514

1Senior Resident, Department of Pathology, PRM Medical College and Hospital, Baripada, Odisha, India

2Associate Professor, Department of Pathology, Government Medical College and Hospital, Sundargarh, Odisha, India

3Associate Professor, Department of Pathology, PRM Medical College and Hospital, Baripada, Odisha, India

4Senior Resident, Department of Pathology, PRM Medical College and Hospital, Baripada, Odisha, India

5Scientist C, Multi Disciplinary Research Unit, PRM. Medical College and Hospital, Baripada, Odisha, India

*Corresponding Author Email: dratanubal1974@yahoo.co.in

Online published on 31 March, 2026.

Abstract

The Paris System aims to create consistent guidelines for reporting urinary tract cytology results. This study evaluated how well these guidelines work and compared them to the outcomes of follow-up biopsies. A total 70 patient were included in this study out of which 80% were male. Most common age of presentation of urinary bladder lesions was between 61–80 years (55.7%).Most common lesion by urinary cyto-diagnosis according to TPS was found to be HGUC 30 (42.9%) followed by NHGUC 15 (21.4%). The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of the Paris system for urine cytology in assessing urinary bladder neoplasm was 79%,70.9%,83.3%,65.4% ,74.3% respectively. TPS standardizes urine cytology criteria, boosting accuracy and reducing equivocal diagnoses (like atypical urothelial cells). This facilitates high-grade urothelial carcinoma (HGUC) detection.

Keywords

Urine cytology, High-grade urothelial carcinoma, Histopathology