Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 12

A Comprehensive Review on Exploring the Therapeutical Potentials of Randia dumetorum Lamk

1School of Pharmacy, Mangalayatan University, Aligarh-202146, India

2Mangalayatan Institute of Pharmaceutical Education and Research, Mangalayatan University, Aligarh - 202146, India

*Corresponding Author E-mail:shubham.skdm@gmail.com

Online Published on 28 May, 2026.

Abstract

Randia dumetorum, a member of the Rubiaceae family, is a well-regarded Ayurvedic medicinal tree. It is commonly referred to as Mainphal or Mindhal. A substantial thorny shrub that sheds its leaves grows to a height of up to 5 metres. It is found throughout most of India, reaching altitudes of up to 4,000 feet. The species is distributed in the Himalayas, ranging from Jammu in the west to an altitude of 1300 metres, and from Kashmir to the east, reaching elevations of up to 4000 metres. The presence of this species has been observed in the forests of Gujarat, Tamil Nadu, Dehradun, the Suralik range, Bengal, Bihar, Orrisa, South Maharashtra, and the coastal areas of South India. Within the arid deciduous woodlands of India. The root bark of Randia dumetorum includes a triterpene known as -1-keto-3-hydroxyoleanane. The bark of Randia dumetorum includes mannitol, saponins, and coumarin glycosides. Leaves possess an iridoid-10-methylixoside compound. An iridoid glycoside is a type of compound. The presence of glycosides, specifically randioside A and mollisidial, as well as pentacyclic triterpenoid glycosides such as oleanolic acid and randianin, has been identified in ripe fruit. Additionally, six saponins, namely dumetoronins A to F, have also been detected. It possesses the ability to heal abscesses, ulcers, inflammation, wounds, tumours, and many skin illnesses. Additionally, it exhibits antimicrobial properties and antifungal properties. This literature contains numerous phytopharmacological evaluations that highlight the significant potential of Randia dumetorum.

Graphical Abstract:

Different Therapeutic Activity shown in Randia dumetorum Lamk.

Keywords

Randia Dumetorum Lamk, Chinese Medicine, Anti-fungal, glycoside, antidiabetic