Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 2

Assessment of Obesity Indices and Cardiovascular Risk Factors in Type 2 Diabetes Mellitus: A Pilot study from a Tertiary care centre in India

  • Author:
  • Darpelly Mahesh1, Gautam Kumar2, Ashok Kumar Gupta3,*, Vijay Kumar Singh4, Veena Devi Singh4
  • Total Page Count: 7
  • Page Number: 878 to 884

1Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER), Hajipur, India

2School of Pharmaceutical Sciences, Apeejay Stya University, Gurugram, Haryana, India

3School of Pharmacy, Sharda University, Knowledge Park-3, Greater Noida, Uttar Pradesh, 201306, India

4Shri Rawatpura Sarkar College of Pharmacy, Shri Rawatpura Sarkar University, Dhaneli, Raipur, Chhattisgarh, 492015, India

Abstract

The ability of obesity indices to predict cardiovascular risk in type 2 diabetes mellitus (T2DM) is still debated. This study aims to assess cardiovascular risk factors with anthropometric characterization and obesity indices.

In this observational cross-sectional study, a total of 181 T2DM patients were recruited. Patients were divided based on body mass index (BMI), where normal weight was classified as Group 1 with BMI < 25 kg/m2, n = 94; and overweight as group 2 with BMI ≥ 25 kg/m2, n = 87. Various parameters and their correlations were assessed such as body adiposity index (BAI), visceral adiposity index (VAI), waist circumference (WC), hip circumference (HC), waist/hip ratio (WHR), waist/height ratio (WHtR), Fasting blood sugar (FBS), Postprandial blood sugar (PPBS), ankle-brachial index (ABI) and cardiovascular disease risk factors.

Out of 181 T2DM patients, 54.1% of the patients were male. Females had higher mean HC, WHtR, BAI, VAI (all P < 0.001), and WC but lower mean height (P < 0.001), weight (P < 0.05), and WHR. Group 2 patients had higher weight, WC, HC, WHtR, and BAI (all P < 0.001) in comparison to Group 1. Among obesity indices, VAI showed the highest correlation (all P < 0.05) with cardiovascular risk factors.

Among all obesity indices VAI showed the highest correlation with cardiovascular risk factors, thus routine measurement of VAI in the clinical setting is advised for the evaluation of T2DM-related complications and cardiovascular risk factors, particularly in women.

Keywords

Ankle-brachial index, Anthropometric characterization, Body mass index, Cardiovascular risk factors, Diabetes, Obesity indices