Association between serum liver enzymes among hypertensive type II diabetes mellitus patients: A cross-sectional study

To assess the relationship between serum liver enzyme activity and other biochemical parameters of liver function test (LFT) among hypertensive patients with Type II diabetes mellitus (T2DM).

The research enrolled 276 participants in total. All of the patients were split into three groups based on their illness states: diabetes (42%), hypertension (HTN) (14.75%) and both (40.25%). Monitoring of blood pressure (BP), blood sugar, and laboratory testing for SGOT, SGPT, ALP, bilirubin, and albumin were all included in the analysis.

High levels of Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), and albumin were more common in females than in men in each group, although raised levels of Alkaline phosphatase (ALP) and bilirubin were more common in males. Diabetic patients with mixed diets had greater instances of elevated LFT values in comparison with vegetarians. A positive correlation is also observed from the data that as the duration of the disease increases LFT values for each category also increases.

These findings imply that people with T2DM and HTN have liver enzyme levels that are noticeably higher. The risk of liver damage may be increased in part by T2DM and HTN.