Evaluation of the Radiographic and Microscopical Impact of Aloe vera Gel Application on Alveolar Bone in Wistar Rats Exposed to Periodontitis

Aloe vera is an herbal ingredient that contains acemannan, aloe emodin, vitamins (B1, B2, B6, B12, and C) and a number of minerals such as calcium, chlorine, chromium, copper, iron, magnesium, manganese, potassium, phosphorus, sodium, and zinc. So it has the potential to overcome bone resorption in periodontitis. This study aims to evaluate the effect of Aloe vera gel preparation on alveolar bone structure radiographically and microscopically in Wistar rats induced periodontitis. Induction of periodontitis was carried out for 14 days with the installation of 0.008 inch wire ligature in the cervical area of the maxillary first molar. In this study, rats were utilized to assess the effectiveness of periodontitis modification. Mice with periodontitis were divided into negative control, positive control group, and treatment group. Each group received gel base, metronidazole gel, and Aloe vera gel preparation. The test substance was applied every morning and evening for 14 days. The statistical analysis revealed a significant difference in alveolar bone density at p = 0.000 (p < 0.05). As a result, Aloevera gel preparation has an effect on the height and density of alveolar bone, as well as the microscopic structure and composition of alveolar bone in Wistar rats with periodontitis.