Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 4

Potential Occurrence of Drug related problems (DRPs) in Type 2 Diabetes Mellitus patients

  • Author:
  • Anna Pradiningsih1,*, Yek M Hasan1, Baiq Leny Nopitasari1, Wirawan Adikusuma1,2
  • Total Page Count: 7
  • Page Number: 1597 to 1603

1Department of Pharmacy, University of Muhammadiyah Mataram, West Nusa Tenggara, Indonesia

2Research Center for Computing, Research Organization for Electronics and Informatics, National Research and Innovation Agency (BRIN), Cibinong, Indonesia

*Corresponding Author E-mail: annapradiningsih@gmail.com

Online Published on 24 July, 2025.

Abstract

Diabetes is a chronic condition that occurs when the pancreas doesn’t produce enough insulin or when the body is unable to effectively use insulin. Therapy for Type 2 Diabetes Mellitus (T2DM) typically begins with oral antidiabetic drugs and the use of combination therapy if blood sugar levels do not decrease. Multiple therapies can potentially lead to Drug Related Problems (DRPs) that affect the effectiveness and safety of the treatment. This study aims to identify DRPs in the Inpatient Department of the Regional General Hospital of West Nusa Tenggara Province. The research used a descriptive observational design, with purposive sampling technique. The required sample size was 88 T2DM patients who met the inclusion and exclusion criteria. The research study was retrospective, based on medical records from January to December 2022. The criteria for DRPs refer to Pharmaceutical Care Network Europe (PCNE) V9.01, processed using Microsoft Excel 2019 software to obtain the percentage of DRPs occurrences. The results showed that out of 88 patients, 61% experienced DRPs with a total of 81 occurrences. The categories of DRPs that occurred, in descending order, were drug interactions (51.9%), drugs without indication (38.3%), untreated indications (7.4%), overdose (1.2%), and incorrect drug, strength, or dosage (1.2%).

Keywords

Diabetes Mellitus, Drug Related Problems, Antidiabetic drugs