Research Journal of Pharmacy and Technology

The Rosmarinus officinalis var. prostrates and Rosmarinus officinalis are important medicinal plant that has been used in folk medicine to treat many diseases, all its parts contain active ingredient but this study focuses on the phenolic content, the anti-oxidant activity, and the chemical composition of the essential oil in The Rosmarinus officinalis var. prostrates and Rosmarinus officinalis leaves ( in kallamoon region, Syria) This study showed that the phenolic content in the ethanolic extract of R. officinalis is (1.6556)mg/1g of dried powder, while the phenolic content in extract of R. officinalis var. prostrates is(1.799)mg/1g dried powder and the Determination of Carnosic acid, O-12-methylcarnosic acid, Rosmarinic acid and Ginquanin by HPLC, has shown that the concentration of Carnosic acid, rosmarinic acid and ginquanin in the extract of R.officinalis var. prostrates is higher than R.officinalis, Additionally the antioxidant capacity value of R. officinalis var. prostrates is higher than R. officinalis in leaf extract, while the antioxidant capacity value of R. officinal is oil is higher than that of R. officinalis var. prostrates using PCL assay, The GC- The GC-MS analysis revealed that the major components in Rosmarinus officinalis var. prostrates essential oil were 1,8-Cineole (42.18%), a-Pinene (11.38%), Camphene (5.39%), a-Humulene (5.63%), p-Cymene (4.98%). Meanwhile the major components in Rosmarinus officinalis were 1,8-Cineole (39.19%), a-Pinene (9.13%), Camphene (4.65%), β-Caryophyllene (4.47%), p-Cymen-8-ol (4.18%), β-Pinene (3.16%)