Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 4

Isolation and Biotesting of Tannins from Eichhornia crassipes plants: Pom analyses and Antifungal/antiviral Pharmacophore sites Identification

  • Author:
  • Gulzira Yernazarova1,*, Aliya Ramazanova2, Svetlana Turasheva1, Danagul Mukasheva3, Madina Amangeldinova1,4, Saltanat Mamanova3, Gulnur Omarova5, Nurken Aimukhanov6, Ishmam Arabi7, Faisal Almalki8, Sarkar Kawsar9, Taibi Ben Hadda10
  • Total Page Count: 11
  • Page Number: 1861 to 1871

1Al Farabi Kazakh National University, Almaty, 050040, Republic of Kazakhstan

10Euromedeterranian University of Fes (UEMF), Meknes Road, 30000, Fez, Morocco

2Kazakh National Women‘s Teacher Training University, Almaty, 050000, Republic of Kazakhstan

3Zhetysu University named after I. Zhansugurov, Taldykorgan, 040009, Republic of Kazakhstan

4Institute of Genetics and Physiology, Almaty, 050040, Republic of Kazakhstan

5Saken Seifullin Kazakh Agrotechnical University, Astana, 010000, Republic of Kazakhstan

6Nazarbayev Intellectual School of Physics and Mathematics, Uralsk, 090000, Republic of Kazakhstan

7Green University of Bangladesh, Dhaka, 1207, Bangladesh

8Umm Al-Qura University, Makkah, 21955, Saudi Arabia

9University of Chittagong, Chittagong-4331, Bangladesh

*Corresponding Author E-mail: gulzira.yernazarova@bk.ru

Online Published on 24 July, 2025.

Abstract

Nutrients produce various secondary metabolites, including biologically active compounds such as antifungals. The composition of E. Crassipes aquatic plant contains biologically active substances. In this article, the composition of substances in E. Crassipes was identified using IR, 1H, and 13C-NMR methods. The identified substances were characterized for biological activity using the PASS online program. This was based on their molecular structure. As a result of the program, compounds showing activity against light, viruses, earwigs, and bacteria were developed. The program’s scope included testing the substances’ antimicrobial activity using agar diffusion assay in experiments. Substances were extracted from the aquatic plant via chromatography-mass spectrometry, and their activity against earwigs was examined. The study revealed efficacy against Candida albicans and Candida utilis earwigs.

Keywords

E. Crassipes, Biologically active substances, Tannins, POM (Petra/Osiris/Molinspiration Theory, Identification of Antiviral/Antifungal pharmacophore sites