Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 5

Current Insights on Preparation Methods and Characterisation of Nanoparticles

Amity Institute of Pharmacy, Lucknow, Amity University, Uttar Pradesh, Sector 125, Noida, 201313, India

*Corresponding Author E-mail: nsrivastava3@lko.amity.edu

Online Published on 29 July, 2025.

Abstract

This review outlines the potential application of nanoparticles as a remedy of drug solubility and bioavailability problems which are the major drawbacks in traditional drug delivery systems. Nanoparticles have the unique characteristics of size, high surface area, and versatility for modulation of their properties for specific functions which help improve the bioactive compound’s pharmacokinetic and pharmacodynamic factors. Nanoparticles improve bioavailability by increasing the solubility of poorly soluble drugs and you get better therapeutic efficacy and fewer side effects. In addition, their ability to target specific tissue locations in the body allows for reduced systemic toxicity and improved therapeutic effects. Research in nanoparticle-based drug delivery is ongoing; however, it is predicted that they will play one of the most significant roles in the future development of such strategies, and their ability to restructure existing drugs represents a change from a mere evolution to maintaining a revolution of the revolution.

Keywords

Nanoparticles, Solubility, Bioavailability, High-Pressure Homogenization, Media Milling, Dissocubes