Research Journal of Pharmacy and Technology

The insecticide Cidamethrin 50 EC is a liquid insect poison containing the active ingredient cypermethrin 50 g/L to eradicate pests on plants. These insecticide residues can pollute waters and enter the fish's body through the gills and have an impact on physiological processes, changes in behavior, larval abnormalities in the form of head deformities, crooked backs, lordosis, scoliosis, kyposis, and death in fish. The aim of this research was to determine the toxicity of the insecticide Cidamethrin 50 EC on abnormal forms of tilapia prolarvae (Oreochromis niloticus L.). This type of experimental research is structured based on a Completely Randomized Design (CRD) pattern. The research method was carried out in stages, namely obtaining tilapia eggs and sperm, maintaining the quality of the rearing container after fertilization. Fertilized eggs were divided into 5 treatments, namely 1 control and 4 doses of insecticide, namely; 0.30 ml/L (P1), 0.35 ml/L (P2), 0.40 ml/L (P3), and 0.45 ml/L (P4), each consisting of 20 items. The insecticide Cidamethrin 50 EC was given for three days and observations were made after the eggs entered the prolarva stage. The observation parameters are the percentage of abnormalities and the shape of the prolarvae abnormalities. Data were analyzed using one way ANOVA (Analysis of Varience) and LSD further test with a confidence level of 95%. The results showed that the insecticide Cidamethrin 50 EC had a toxic effect on increasing the percentage of abnormal tilapia prolarvae. The average percentage of abnormalities for each treatment is: 20% (P1), 45% (P2), 70% (P3) and 75% (P4). Forms of abnormalities found include; lordosis, kyphosis, scoliosis, rolled tail and stuck tail. The conclusion of this research is that the toxicity of the insecticide Cidamethrin 50 EC causes various forms of abnormalities in tilapia prolarvae.