Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 7

Oral Delivery of Lipid Nanosystem: Pharmacokinetics and Pharmacodynamic Advances

  • Author:
  • Omkar Salunkhe1,*, Namdeo Jadhav2, Ashok Hajare3, Shiju Sebastian4, Punam Kumari5, Puja Malhotra6
  • Total Page Count: 9
  • Page Number: 3444 to 3452

1Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth, Karad, Maharashtra, India415539

2Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth, Karad, Maharashtra, India415539

3Bharati Vidyapeeth College of Pharmacy, Palus, Maharashtra, India416313

4Christ Deemed to be University, Bangalore, Karnataka, India560029

5School of Computer Science Engineering and Technology, Bennett University, GN (UP), India201310

6Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India122505

*Corresponding Author E-mail: omkarsalunkhekvv@outlook.com

Online Published on 08 October, 2025.

Abstract

Nanolipid-based drug delivery systems are a new milestone to be achieved in the field of pharmaceutical science as it integrates the advantages of lipid carriers with nanoscale features. The oral administration of such systems promises better drug bioavailability, targeted delivery, and novel sustained release profiles which help in overcoming the physiological hurdles posed by the gastrointestinal tract. Formulation stability and therapeutic efficacy have recently seen improvement alongside promising preclinical results. Regulatory frameworks are also starting to appreciate the potential these novel carriers offer. There seems to be a paradigm shift as evolution in the field would foster intelligent personalized therapies for increased patient care. Enhanced therapy will integrate smart delivery systems alongside scalable nanolipid system manufacturing.

Keywords

Pharmacokinetics, Pharmacodynamic, Lipid nano-systems, Drug targeting