Research Journal of Pharmacy and Technology

An interesting field of research that blends nanotechnology with medicine is the use of green metallic nanoparticles to treat neurological illnesses. Metallic nanoparticles have a number of benefits, including biocompatibility, low toxicity, and ease of synthesis, especially when they are produced using green synthesis techniques. The complex pathophysiologic disorder known as metabolic syndrome is mostly brought on by an imbalance in the amount of energy expended and calories consumed. Natural substances, particularly plant extracts, are thought to be a good alternative for treating metabolic disorders because of their low risk of adverse effects and their antioxidant, anti-inflammatory, and insulin-sensitizing qualities. However, these botanicals’ poor solubility, low bioavailability, and volatility make them less effective. Due to these particular constraints, an effective system is required that lowers medication loss and degradation, gets rid of undesirable side effects, increases drug bioavailability and increases the amount of the drug that is deposited in the intended locations. Green-engineered nanoparticles have been created in the pursuit of a more efficient medication delivery mechanism, and this has improved the solubility, stability, bioavailability and biological distribution of plant-based products. The combination of metallic nanoparticles and plant extracts has aided in the creation of novel treatments for metabolic diseases such cancer, diabetes mellitus, obesity, neurodegenerative diseases, and non-alcoholic fatty liver. This review describes the pathophysiology of metabolic illnesses and how plant-based Nano medicine can treat them. However, it’s crucial to remember that study is still needed to fully understand the potential advantages, safety, and efficacy of metallic nanoparticles in clinical applications. The field of Nano medicine, including the use of these particles for neurological illnesses, is still in its early stages. However, before these technologies are extensively used in clinical practice, obstacles such ensuring precise targeting, avoiding adverse effects, and addressing regulatory impediments must be addressed.