Harnessing Multi-walled Carbon Nanotubes to Overcome Cancer Resistance: Utility and Challenges

Cancer resistance is a major problem affecting drug management in chemotherapy, which results to relapse and tumour regrowth. At present, alterations still occur and continue to pose a major problem because of genetic, epigenetic, proteomic, metabolic, microenvironment, and other causes. Multi walled carbon nanotubes will be another prospect towards surmounting this; resistance. These structures are based on carbon atoms arranged in hexagonal lattices; due to specific thermal and mechanical characteristics, they can be used as reinforcements. The possibility which lies in the application of nanoparticles to increase drug delivery and the effectiveness of the latter in cancer treatment indicates the need for the development of a new strategy for overcoming cancer resistance mechanisms. Thus, this review aims at revealing the potential of Multi walled carbon nanotubes in consideration of drug-resistant diseases and opening the discussion on the topic for further detailed investigation.