Evaluation of Antioxidant and Antibacterial activities of Atylosia rugosa

The present study was designed to study the in vitro antioxidant activity and antibacterial activities of Atylosia rugosa. The antioxidant activities of the extracts were examined using different biochemical assays namely diphenlpicrylhydrazyl (DPPH), hydrogen peroxide radical scavenging activity and the antibacterial activity of the extracts was also evaluated and MIC values were calculated by broth dilution method. The assays, revealed that the ethyl acetate extract exhibited stronger antioxidant activity than that of ethanolic extract, the extracts also prevented the growth of both Gram positive and Gram negative bacteria, the MIC values of ethanolic extract has higher antibacterial than those of the ethyl acetate. The antioxidant and antibacterial activity of the extracts was found to be positively associated with the total phenolic and favonoid content of the extracts. A positive, significant linear relationship between antioxidant activity and TPC and TFC content showed that phenolic compounds and flavonoids were the dominant and possessing antioxidant and antibacterial properties of Atylosia rugosa.