Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2025
  • Volume: 18
  • Issue: 9

Antibacterial effect of Pylantus niruri L. (Meniran) from Indonesia toward Staphylococcus epidermidis and Phytochemical Screening

  • Author:
  • Em Sutrisna1,*, Wahyuni1, R Usdiana Devi1, Noor Fadzilah Zulkifli2, Nazefah Abd Hamid2, Siti Salhah Othman3, Farah Wahida Harun3, Dzulfadli Rosli4
  • Total Page Count: 5
  • Published Online: Dec 19, 2025
  • Page Number: 4477 to 4481

1Medical Faculty of Universitas MuhammadiyahSurakarta, Indonesia

2Faculty of Medicine and Health Science of University Sains Islam Malaysia, Malaysia

3Faculty of Science and Technology, University Sains Islam Malaysia, Malaysia

4Institue of Fatwa and Halal, University Sains Islam Malaysia, Malaysia

*Corresponding Author E-mail: es233@ums.ac.id

Online published on 19 December, 2025.

Abstract

In Indonesia there is no antibacterial medicine based on Indonesian medicinal plants Pylantus niruri L. (Meniran) is allegedly to have an antibacterial effect.

This study aims to explore the antibacterial effects of the 96% ethanolic extract of P.niruri and to determine it’s TLC [Thin layer chromatography]

The test design is an invitro study with diffusion and well methods. Bacteria used is S. epidermidis. The plant also performed phytochemical screening to determine the plant content that was suspected to have an antibacterial effect and continued thin layer chromatography.

The 96% ethanolic extract of P.niruri at concentrations of 100; 50; 25; 12.5 and 6,125% have an antibacterial effect with inhibition zones of 12,5;18,41; 12,31; 11,09 and 8,83mm.

P niruri L. has potency antibacterial toward S. epidermidis

Keywords

Meniran, P. niruri, Staphylococcus Epidermidis, Antibacterial