1Raj Kumar Goel Institute of Technology (Pharmacy), 5-KM. Stone, Delhi-Meerut Road, Ghaziabad, Uttar Pradesh, India
2Department of Pharmaceutics, Delhi Pharmaceutical Sciences and Research University, New Delhi110017, India
3School of Pharmacy, Sharda University, Greater Noida, Uttar Pradesh201310(U.P.)
*Corresponding Author E-mail: meghafrnds@gmail.com
Online published on 19 December, 2025.
In light of the challenges of creating novel drug molecules, more focus is being placed on developing innovative methods for delivering pre-existing drugs. Due to significant batch-to-batch variability, the production of nanoparticle-based drug delivery systems is still in its infancy. This is impeding industrial-scale clinical translation even though several techniques have been discovered. Thus, it is not surprising to see this technique advance slowly, this is not the case when it comes to the controlled-release drug delivery mechanism. The principal aims of this study are to investigate recent advancements in formulation techniques, deliberate on tactics to improve controlled drug administration, and underscore the possibilities of these systems for targeted drug delivery. This manuscript discusses controlled drug delivery systems, focusing on preparation approaches, recent advancements, patents, marketed preparations, challenges, and future perspectives.
Controlled-Release Drug Delivery, Dissolution, Diffusion, Polymers, Patents