Exploring the Diverse Pharmacological Potential of Glycyrrhiza glabra Root and Terminalia chebula Fruit Extracts

Natural remedies have always been abundant in nature, providing us with a wide range of therapeutic plants that yield beneficial phytochemicals. One common herb used in ayurveda is G. glabra. Terminalia chebula is sometimes referred to as the black myrobalan, ink tree, and chebulic myrobalan. The current study’s objectives were to assess the exploring diverse of pharmacological potential of glycyrrhiza glabra root and terminalia chebula fruit extracts by phytochemicals, antioxidant, antidiabetic, antifungal, anti-inflammatory, anticancer activities MTT assay. Antioxidant activity was measured using the reduction test and by radical scavenging assay. For G. glabra and T. chebula, the highest DPPH˞ radical scavenging activity was 67.66±0.95% and 80.04 ±0.95% at 120μg/mL concentration in the aqueous extract. superoxide radical scavenging activity of Glycyrrhiza glabra and Terminalia chebula was 80.95±0.40% and 76.56±0.45%, respectively, while the IC50 was 80μg/mL and 105.6 μg/mL. Superoxide radical scavenging activity of Glycyrrhiza glabra and Terminalia chebula was 80.95±0.40% and 76.56±0.45%, respectively, while the IC50 was 80 μg/mL and 105.6μg/ml. Phosphomolybdenum reduction was 195.51±0.75% and 134.51±0.12%, respectively, and the RC50 was 64.55μg/mL and 12.93μg/mL concentration. Fe3⁺ reduction was 162.02±0.40% and 196.03±0.75%, respectively, and the RC50 was 49.34μg/mL and 8.5μg/mL concentration. 100μg/mL resulted in a maximal zone of inhibition of 21mm for Staphylococcus aureus. The greatest zone of inhibition for Candida krusei measured 19mm for antifungal activity.