1Residence in Periodontic Program, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
2Department of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
3Department of Oral and Dental Medicine, Faculty of Medicine, Taiz University, Taiz, Yemen
4Faculty of Oral and Dental Medicine, Al-Saeed University, Taiz, Yemen
*Corresponding Author E-mail: chiquita-p-s@fkg.unair.ac.id
Online Published on 29 May, 2026.
Bone graft materials are commonly used to promote successful periodontal tissue treatments. However, these materials have various drawbacks while being widely utilized. A recent study focuses on tooth grafts to address the flaw. This study compared osteocalcin expression in bone healing following incisor extraction socket grafting with tooth graft and xenograft hydroxyapatite.
The study conducted experiments on thirty-three adult male Cavia cobaya randomly divided into hydroxyapatite tooth graft, hydroxyapatite xenograft, and control group (no treatment). Bone tissue sections were stained with hematoxylin-eosin and diaminobenzidine to analyze osteocalcin expression through immunohistochemical evaluation.
The Kruskal-Wallis test was used to compare each group, with a significance level of p=0.05. The results revealed a significant difference in mean osteocalcin between groups (p < 0.05). Osteocalcin expression was higher in the tooth graft group and lowered in the control group.
The findings indicate that tooth grafts hold great potential as a new material for bone grafting, given their osteoinductive and osteoconductive properties, which are comparable to those of xenografts.
Hydroxyapatite, Human, Health, Osteocalcin, Tooth graft, Xenograft
